July 2022 Updates

FACULTY SCHOLARSHIP

Publications

United States Transuranium and Uranium Registries (USTUR) Director and Professor Sergei Tolmachev and two co-authors published “Quadrupole and multi-collector ICP-MS analysis of 226Ra in brain from a radium dial painter,” in the Journal of Analytical Atomic Spectrometry.

Pharmaceutical sciences and molecular medicine students Deepak Ahire (Prasad lab), Laken Kruger (Prasad lab), and Sheena Sharma (Prasad lab), with faculty co-authors Pharmaceutical Sciences Research Associate Vijaya Saradhi Mettu (Prasad lab) and Pharmaceutical Sciences Associate Professor Bhagwat Prasad and one co-author published, “Quantitative Proteomics in translational absorption, distribution, metabolism, and excretion and precision medicine,” in Pharmacological Reviews in July 2022.

Laken Kruger, with faculty co-authors Pharmaceutical Sciences Associate in Research Guihua Yue (associate in research, Prasad lab), Vijaya Saradhi Mettu, Bhagwat Prasad, and two co-authors published, “Differential proteomics analysis of JEG-3 and JAR placental cell models and the effect of androgen treatment,” in the June 2022 issue of The Journal of Steroid Biochemistry and Molecular Biology, a peer-reviewed scientific journal covering all aspects of steroid metabolism.

Pharmacotherapy Vice Chair & Allen I. White Distinguished Professor Joshua Neumiller and two co-authors published, “Management of chronic kidney disease in type 2 diabetes: screening, diagnosis and treatment goals, and recommendations,” in Postgraduate Medicine.

Service

Bhagwat Prasad has been named senior editor of the journal Pharmacology Research & Perspectives, serving a three-year term. The bimonthly, open-access journal is jointly published by the American Society for Pharmacology and Experimental Therapeutics (ASPET), the British Pharmacological Society (BPS), and publishing company Wiley.

Grants & Awards

2022 College of Pharmacy and Pharmaceutical Sciences Faculty and Staff Excellence Awards were presented during the 2022 retreat on July 22, 2022:

  • Excellence in Teaching award, Pharmaceutical Sciences Associate Professor Sue Marsh
  • Excellence in Service award, Pharmaceutical Sciences Assistant Professor Travis Denton
  • Staff Excellence Award, Instruction and Classroom Support Technician Jill Morin
  • Staff Excellence Award, Fiscal Specialist from Business Services Marnie Staples (Rogers)

Bhagwat Prasad has been awarded a $150K contract with Takeda Millennium, a pharmaceutical company focused on the discovery and development of medications for cancer treatment. The funding supports a project that is part of the Proteomics-based Research Initiative for Non-CYP Enzymes (PRINCE), a research collaboration between Washington State University and pharmaceutical companies Genentech, Gilead, and Takeda. The project is aimed at improving the predictability of drug metabolism and drug interaction of new candidate drugs. Non-cytochrome P450 (non-CYP) enzymes play an important role in the metabolism of many drugs. When drug metabolism findings in non-CYP enzymes cannot be reliably extrapolated from an in vitro environment (i.e., test tube or petri dish) to in vivo (a living organism), this results in unpredictable pharmacokinetics and safety of drugs. To address these challenges, Prasad and his team will test a novel in vitro to in vivo extrapolation approach in both an in vitro system and human tissues.

STUDENT ACHIEVEMENT          

Pharmaceutical Sciences and Molecular Medicine students

Deepak Ahire (Prasad lab), Laken Kruger (Prasad lab), and Sheena Sharma (Prasad lab), with faculty co-authors Pharmaceutical Sciences Research Associate Vijaya Saradhi Mettu (Prasad lab) and Pharmaceutical Sciences Associate Professor Bhagwat Prasad and one co-author published, “Quantitative Proteomics in translational absorption, distribution, metabolism, and excretion and precision medicine,” in Pharmacological Reviews in July 2022.

Laken Kruger, with faculty co-authors Pharmaceutical Sciences Associate in Research Guihua Yue (associate in research, Prasad lab), Vijaya Saradhi Mettu, Bhagwat Prasad, and two co-authors published, “Differential proteomics analysis of JEG-3 and JAR placental cell models and the effect of androgen treatment,” in the June 2022 issue of The Journal of Steroid Biochemistry and Molecular Biology, a peer-reviewed scientific journal covering all aspects of steroid metabolism.